Applied Research

 

Applied Research

 NENEXP

The NENEXP project is a multi-centre cohort study of mothers and children exposed to antiretroviral treatment during pregnancy.

The objectives are: 

  1. to quantify and monitor the rate of mother-to-child transmission of HIV; 

  2. to identify the clinical, epidemiological and biological factors associated with mother-to-child transmission in our setting; 

  3. and to monitor the possible negative effects in children exposed to antiretroviral treatment during pregnancy and early childhood.

 Data have been collected from all HIV positive mothers and their newborns in 8 hospitals in Madrid and 4 in Barcelona from January 2000. These data include demographic, clinical and biological data collected during pregnancy, at childbirth, and at 2, 8, 12, and 24 weeks of life of the newborn, and then every 12 months.

Both initial projects, that have been made between the 1st of January of 2000 and the 31st of December of 2002, has been prorogued by 6 years more (FIPSE 36352/02 and 36535/05 for Catalonia and 36299/02 and 36531/05 for Madrid), enlarging inclusion criteria for NENEXP study from HIV positive pregnant women, and does not have to start off of exposed newborn. Consequently, the follow-up of the pregnancy as the evolution of the children are prospective. Since the beginning, these multi-centre projects were included into the Paediatric Line from the Spanish AIDS Research Network (RIS) del FIS-Ministry of Health (Groups network number 173).

 

Internal documentation of NENEXP project

Demo NENEXP

Link to the Registry of the Cohort of HIV infected mother-infants pairs

Related Text in SIVES-2004 (PDF) New

Symposium. Challenges for future: The prevention of HIV mother-to-child transmission in Catalonia (NENEXP Project) 21 June 2006. Sala d’Actes. Departament de Salut. Generalitat de Catalunya New

Project Leader: Jesús Almeda; Joan Masip